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Red-emitting fluorescent organic@silicate core-shell nanoparticles towards bio-imaging

Abstract

We demonstrate here that the encapsulation of crystal-state emitters in sol-gel matrices is an efficient way to produce bright nanotracers for bioimaging applications. We report the development of a family of fluorescent organic@silicate core-shell nanoparticles (NPs) containing an organic core surrounded by a silicate shell, with a high loading of dyes (30-40%wt), and prepared by an original spray-drying technique combining sol-gel chemistry and nanocrystallization. Four dyes were encapsulated within silicate nanoparticles. The crystallinity of the organic core is discussed on the basis of characterizations by electron microscopy and fluorescence spectroscopy. Bright, red-emitting core-shell NPs have been produced, which are promising for use in bio-imaging.

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Publication details

The article was received on 02 Jul 2018, accepted on 06 Aug 2018 and first published on 07 Aug 2018


Article type: Paper
DOI: 10.1039/C8NJ03297A
Citation: New J. Chem., 2018, Accepted Manuscript
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    Red-emitting fluorescent organic@silicate core-shell nanoparticles towards bio-imaging

    S. Shenoi-Perdoor, X. Cattoen, Y. Bretonnière, G. Eucat, C. Andraud, B. Gennaro, S. Kodjikian, F. Dubois and A. Ibanez, New J. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8NJ03297A

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