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Scope of regioselective Suzuki reactions in the synthesis of arylpyridines and benzylpyridines and subsequent intramolecular cyclizations to azafluorenes and azafluorenones

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Abstract

The current investigation on regioselective Suzuki reactions of 2,3-dihalopyridines and 2-halo-3-halomethylpyridines yielded the unexplored synthesis of arylpyridines and benzylpyridines bearing synthetic handles for further functionalization. Indeed, the scope of intramolecular cyclizations of arylpyridines and benzylpyridines prepared in this study for the synthesis of azafluorenes and azafluorenones has been investigated.

Graphical abstract: Scope of regioselective Suzuki reactions in the synthesis of arylpyridines and benzylpyridines and subsequent intramolecular cyclizations to azafluorenes and azafluorenones

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Publication details

The article was received on 01 Jun 2018, accepted on 22 Aug 2018 and first published on 22 Aug 2018


Article type: Paper
DOI: 10.1039/C8NJ02734J
Citation: New J. Chem., 2018, Advance Article
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    Scope of regioselective Suzuki reactions in the synthesis of arylpyridines and benzylpyridines and subsequent intramolecular cyclizations to azafluorenes and azafluorenones

    J. K. Laha, K. V. Patel, Saima, S. Pandey, G. Solanke and V. Vashisht, New J. Chem., 2018, Advance Article , DOI: 10.1039/C8NJ02734J

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