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Issue 14, 2018
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Efficient synthetic procedure to new 2-imino-1,3-thiazolines and thiazolidin-4-ones promoted by acetonitrile electrogenerated base

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Abstract

A novel and convenient strategy is described for the regioselective conversion of N,N′-disubstituted thioureas and 1,2-dielectrophiles into the highly biologically valuable 2-imino-thiazoline and 2-imino thiazolidine-4-one derivatives. The synthesis proceeds through a process with good yield promoted by an electrogenerated base (EGB) obtained with high current efficiency.

Graphical abstract: Efficient synthetic procedure to new 2-imino-1,3-thiazolines and thiazolidin-4-ones promoted by acetonitrile electrogenerated base

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Publication details

The article was received on 24 Apr 2018, accepted on 11 Jun 2018 and first published on 20 Jun 2018


Article type: Paper
DOI: 10.1039/C8NJ01992D
Citation: New J. Chem., 2018,42, 11776-11781
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    Efficient synthetic procedure to new 2-imino-1,3-thiazolines and thiazolidin-4-ones promoted by acetonitrile electrogenerated base

    B. Haouas, N. Sbei, H. Ayari, M. L. Benkhoud and B. Batanero, New J. Chem., 2018, 42, 11776
    DOI: 10.1039/C8NJ01992D

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