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Lift-off cell lithography for cell patterning with clean background

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Abstract

We developed a highly efficient method for patterning cells by a novel and simple technique called lift-off cell lithography (LCL). Our approach borrows the key concept of lift-off lithography from microfabrication and utilizes a fully biocompatible process to achieve high-throughput, high-efficiency cell patterning with nearly zero background defects across a large surface area. Using LCL, we reproducibly achieved >70% patterning efficiency for both adherent and non-adherent cells with <1% defects in undesired areas.

Graphical abstract: Lift-off cell lithography for cell patterning with clean background

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Publication details

The article was received on 11 Jul 2018, accepted on 30 Aug 2018 and first published on 31 Aug 2018


Article type: Communication
DOI: 10.1039/C8LC00726H
Citation: Lab Chip, 2018, Advance Article
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    Lift-off cell lithography for cell patterning with clean background

    C. Wu, X. Zhu, T. Man, P. Chung, M. A. Teitell and P. Chiou, Lab Chip, 2018, Advance Article , DOI: 10.1039/C8LC00726H

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