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Omnipotent phosphorene: a next-generation, two-dimensional nanoplatform for multidisciplinary biomedical applications

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Abstract

Phosphorene, also known as single- or few-layer black phosphorus (FLBP), is a new member of the two-dimensional (2D) material family and has attracted significant attention in recent years for applications in optoelectronics, energy storage and biomedicine due to its unique physicochemical properties and excellent biocompatibility. FLBP is regarded as a potential biological imaging agent for cancer diagnosis due to its intrinsic fluorescence (FL) and photoacoustic (PA) properties and negligible cytotoxicity. FLBP-based photothermal and photodynamic therapies have emerged with excellent anti-tumour therapeutic efficacies due to their unique physical properties, such as near-infrared (NIR) optical absorbance, large extinction coefficients, biodegradability and reactive oxygen species (ROS) or heat generation upon light irradiation. Furthermore, FLBP is a promising drug delivery platform because of its high drug-loading capacity due to its puckered layer structure with an ultralarge surface area, and FLBP is size-controllable with facile surface chemical modification. Because of the marked advantages of FLBP nanomaterials in biomedical applications, an overview of the latest progress and paradigms of FLBP-based nanoplatforms for multidisciplinary biomedical applications is presented in this tutorial review.

Graphical abstract: Omnipotent phosphorene: a next-generation, two-dimensional nanoplatform for multidisciplinary biomedical applications

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Publication details

The article was received on 30 Apr 2018 and first published on 08 Jun 2018


Article type: Tutorial Review
DOI: 10.1039/C8CS00342D
Citation: Chem. Soc. Rev., 2018, Advance Article
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    Omnipotent phosphorene: a next-generation, two-dimensional nanoplatform for multidisciplinary biomedical applications

    M. Qiu, W. X. Ren, T. Jeong, M. Won, G. Y. Park, D. K. Sang, L. Liu, H. Zhang and J. S. Kim, Chem. Soc. Rev., 2018, Advance Article , DOI: 10.1039/C8CS00342D

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