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Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management

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Abstract

The development of photoactive and biocompatible nanomaterials is a current major challenge of materials science and nanotechnology, as they will contribute to promoting current and future biomedical applications. A growing strategy in this direction consists of using biologically inspired hybrid materials to maintain or even enhance the optical properties of chromophores and fluorophores in biological media. Within this area, porphyrinoids constitute the most important family of organic photosensitizers. The following extensive review will cover their incorporation into different kinds of photosensitizing biohybrid materials, as a fundamental research effort toward the management of light for biomedical use, including technologies such as photochemical internalization (PCI), photoimmunotherapy (PIT), and theranostic combinations of fluorescence imaging and photodynamic therapy (PDT) or photodynamic inactivation (PDI) of microorganisms.

Graphical abstract: Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management

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Publication details

The article was received on 28 Jun 2018 and first published on 28 Aug 2018


Article type: Review Article
DOI: 10.1039/C7CS00554G
Citation: Chem. Soc. Rev., 2018, Advance Article
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    Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management

    V. Almeida-Marrero, E. van de Winckel, E. Anaya-Plaza, T. Torres and A. de la Escosura, Chem. Soc. Rev., 2018, Advance Article , DOI: 10.1039/C7CS00554G

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