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Role of hydrogen bonding in cocrystal and coamorphous solids: Indapamide as a case study

Abstract

The stronger sulfonamide-pyridine (SO2NH2•••N-Py) and sulfonamide-carboxamide (SO2NH2•••O=C-NH) hydrogen bonding directs the formation of cocrystals while weaker sulfonamide-amine (SO2NH2•••N-H) hydrogen bond results in coamorphous products. IDP-PIP and IDP-ARG coamorphous solids exhibit remarkable stability under accelerated conditions.

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Publication details

The article was received on 02 Jul 2018, accepted on 01 Aug 2018 and first published on 07 Aug 2018


Article type: Communication
DOI: 10.1039/C8CE01075G
Citation: CrystEngComm, 2018, Accepted Manuscript
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    Role of hydrogen bonding in cocrystal and coamorphous solids: Indapamide as a case study

    A. Nangia, S. Allu, K. Suresh, G. Bolla and C. Mannava, CrystEngComm, 2018, Accepted Manuscript , DOI: 10.1039/C8CE01075G

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