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Issue 27, 2018
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Cocrystal formation by ionic liquid-assisted grinding: case study with cocrystals of caffeine

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Abstract

Liquid assisted grinding using imidazolium-based ionic liquids (IL-AG) was found to be effective in isolation of cocrystals and cocrystal polymorphs. Isolation of specific polymorphs of caffeine–citric acid (CAFCA) and caffeine–glutaric acid (CAFGLU) cocrystals highlights the tunability of ILs in polymorphic control.

Graphical abstract: Cocrystal formation by ionic liquid-assisted grinding: case study with cocrystals of caffeine

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Publication details

The article was received on 23 May 2018, accepted on 12 Jun 2018 and first published on 20 Jun 2018


Article type: Communication
DOI: 10.1039/C8CE00859K
Citation: CrystEngComm, 2018,20, 3817-3821
  • Open access: Creative Commons BY-NC license
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    Cocrystal formation by ionic liquid-assisted grinding: case study with cocrystals of caffeine

    A. Mukherjee, R. D. Rogers and A. S. Myerson, CrystEngComm, 2018, 20, 3817
    DOI: 10.1039/C8CE00859K

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