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Issue 15, 2018
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Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

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Abstract

Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.

Graphical abstract: Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

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Publication details

The article was received on 12 Dec 2017, accepted on 24 Jan 2018 and first published on 25 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC09518J
Citation: Chem. Commun., 2018,54, 1869-1872
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    Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

    M. D. Wallace, N. F. Waraich, A. W. Debowski, M. G. Corral, A. Maxwell, J. S. Mylne and K. A. Stubbs, Chem. Commun., 2018, 54, 1869
    DOI: 10.1039/C7CC09518J

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