Jump to main content
Jump to site search


Cell penetrating peptide induces self-reproduction of phospholipid vesicles: understanding the role of bilayer rigidity

Abstract

Model lipid vesicles self-reproduce to generate unilamellar daughter vesicles in presence of a cell penetrating peptide. Fluorescence lifetime and anisotropy image analysis exquisitely capture the change in lipid bilayer rigidity throughout the process whereas solvation dynamic study delineates the change in dynamics of the encapsulated water inside vesicles. Overall, our results provide an experimental underpinning of the role of lipid bilayer structural changes in self-reproduction which can exhibit great potential to interpret the protein-membrane interaction in emergence of life and develop new therapeutic strategies.

Back to tab navigation

Supplementary files

Publication details

The article was accepted on 14 Sep 2018 and first published on 14 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC07176D
Citation: Chem. Commun., 2018, Accepted Manuscript
  •   Request permissions

    Cell penetrating peptide induces self-reproduction of phospholipid vesicles: understanding the role of bilayer rigidity

    P. Banerjee, S. Pal, N. Kundu, D. Mondal and N. Sarkar, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC07176D

Search articles by author

Spotlight

Advertisements