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Issue 65, 2018
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Real-time tracing the changes in the intracellular pH value during apoptosis by near-infrared ratiometric fluorescence imaging

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Abstract

We developed a near-infrared ratiometric fluorescent nanoprobe with single-excitation dual-emission. The proposed nanoprobe was applied for real-time monitoring the changes in the pH value during hydrogen peroxide-induced apoptosis by ratio imaging. The pH value of HeLa cells changed from 6.6 to 5.6 after H2O2 (100 μM) stimulation for 40 min.

Graphical abstract: Real-time tracing the changes in the intracellular pH value during apoptosis by near-infrared ratiometric fluorescence imaging

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Publication details

The article was received on 04 Jul 2018, accepted on 23 Jul 2018 and first published on 23 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC05385E
Citation: Chem. Commun., 2018,54, 9071-9074
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    Real-time tracing the changes in the intracellular pH value during apoptosis by near-infrared ratiometric fluorescence imaging

    L. Lin, J. Zhao, L. Zhang, Y. Huang, F. Ye and S. Zhao, Chem. Commun., 2018, 54, 9071
    DOI: 10.1039/C8CC05385E

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