Lanthanide-doped core–shell nanoparticles as a multimodality platform for imaging and photodynamic therapy

Feiya Xu; Yiming Zhao; Min Hu; Pu Zhang; Ning Kong; Ruiyu Liu; Chengcheng Liu; Seok Ki Choi

doi:10.1039/C8CC05057K

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Lanthanide-doped core–shell nanoparticles as a multimodality platform for imaging and photodynamic therapy†

Feiya Xu,

^a Yiming Zhao,

^a Min Hu,

*^a Pu Zhang,

^b Ning Kong,

^b Ruiyu Liu,

^a Chengcheng Liu

*^c and Seok Ki Choi

Author affiliations

* Corresponding authors

^a Department of Chemistry, School of Science, Xi’an Jiaotong University, Xi’an, China
E-mail: humin1971@mail.xjtu.edu.cn

^b School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, China

^c Department of Pathogenic Microbiology & Immunology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’ an, China
E-mail: liuchengcheng@mail.xjtu.edu.cn

^d Department of Internal Medicine, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109-1055, USA

Abstract

We report a novel lanthanide-doped core–shell nanostructure NaYF₄:Yb,Er@NaGdF₄:Nd@SiO₂-RB with a unique design feature that integrates luminescence imaging in biological window II, magnetic resonance imaging, and NIR-excited photodynamic antimicrobial chemotherapy, in a single nanoscale entity.

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Article information

DOI: https://doi.org/10.1039/C8CC05057K
Article type: Communication
Submitted: 25 Jun 2018
Accepted: 28 Jul 2018
First published: 03 Aug 2018

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Chem. Commun., 2018,54, 9525-9528

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Lanthanide-doped core–shell nanoparticles as a multimodality platform for imaging and photodynamic therapy

F. Xu, Y. Zhao, M. Hu, P. Zhang, N. Kong, R. Liu, C. Liu and S. K. Choi, Chem. Commun., 2018, 54, 9525 DOI: 10.1039/C8CC05057K

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Chemical Communications

Lanthanide-doped core–shell nanoparticles as a multimodality platform for imaging and photodynamic therapy†

Abstract

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Lanthanide-doped core–shell nanoparticles as a multimodality platform for imaging and photodynamic therapy

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