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Copper-mediated intramolecular aminofluorination of 1,3-dienes by using nucleophilic fluorine reagent

Abstract

A copper-mediated intramolecular aminofluorination of 1,3-dienes is disclosed, in which both AgF and Et3N•3HF can be used as the fluorine source. This protocol provides a variety of pyrrolidines bearing allylic fluorides with excellent regioselectivities and good diastereoselectivities

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Publication details

The article was received on 20 Jun 2018, accepted on 11 Jul 2018 and first published on 11 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC04909B
Citation: Chem. Commun., 2018, Accepted Manuscript
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    Copper-mediated intramolecular aminofluorination of 1,3-dienes by using nucleophilic fluorine reagent

    G. Liu, Z. Zhang and P. Chen, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC04909B

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