Jump to main content
Jump to site search


Palladium-catalyzed enantioselective carboannulation of 1,3-dienes with aryl iodides enables access to chiral indanes

Author affiliations

Abstract

A palladium-catalyzed enantioselective carboannulation of 1,3-dienes and aryl iodides has been established by using a BINOL-based phosphoramidite ligand. This reaction proceeded via a tandem Heck-type insertion and asymmetric intramolecular Tsuji–Trost allylic alkylation, providing indane derivatives with high levels of enantioselectivity (up to >99% ee).

Graphical abstract: Palladium-catalyzed enantioselective carboannulation of 1,3-dienes with aryl iodides enables access to chiral indanes

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Jun 2018, accepted on 30 Jul 2018 and first published on 31 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC04641G
Citation: Chem. Commun., 2018, Advance Article
  •   Request permissions

    Palladium-catalyzed enantioselective carboannulation of 1,3-dienes with aryl iodides enables access to chiral indanes

    X. Wu, S. Chen, L. Zhang, H. Wang and L. Gong, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC04641G

Search articles by author

Spotlight

Advertisements