Jump to main content
Jump to site search


Unexpected Reactivity of cyclic Perfluorinated Iodanes with Electrophiles

Abstract

We have found that cyclic perfluorinated iodanes react with electrophiles (E+ = Br, Cl, F, I) to afford perfluorinated E-RF compounds. This reactivity is unexpected, since cyclic perfluorinated iodanes are considered as electrophilic reagents that normally react with nucleophiles (e.g. Nu = SR, OR) to afford Nu-RF products. The utility of this new transformation is demonstrated for a [18F]CF3CF2-containing compound which was prepared from [18F]XeF2 obtained from cyclotron produced [18F]fluoride.

Back to tab navigation

Supplementary files

Publication details

The article was received on 07 Jun 2018, accepted on 13 Jul 2018 and first published on 13 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC04558E
Citation: Chem. Commun., 2018, Accepted Manuscript
  •   Request permissions

    Unexpected Reactivity of cyclic Perfluorinated Iodanes with Electrophiles

    S. Gruber, S. M. Ametamey and R. Schibli, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC04558E

Search articles by author

Spotlight

Advertisements