Issue 65, 2018

Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS

Abstract

Fast (>100 kHz) magic angle spinning solid-state NMR allows combining high-sensitive proton detection with the absence of an intrinsic molecular weight limit. Using this technique we observe for the first time narrow 1H RNA resonances and assign nucleotide spin systems with only 200 μg of uniformly 13C,15N-labelled RNA.

Graphical abstract: Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS

Supplementary files

Article information

Article type
Communication
Submitted
05 Jun 2018
Accepted
28 Jun 2018
First published
28 Jun 2018
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2018,54, 8972-8975

Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS

A. Marchanka, J. Stanek, G. Pintacuda and T. Carlomagno, Chem. Commun., 2018, 54, 8972 DOI: 10.1039/C8CC04437F

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