Jump to main content
Jump to site search


Copper(I)-catalyzed N–H olefination of sulfonamides for N-sulfonyl enaminone synthesis

Author affiliations

Abstract

This communication reports copper-catalyzed N–H olefination of sulfonamides for enaminone synthesis using saturated ketones as olefin sources. With TEMPO derivatives and O2 as oxidants, this method provided an efficient way to produce various enaminones in good yields. Mechanistic studies helped figure out the stable intermediates and develop novel methodologies for the difunctionalization of saturated ketones.

Graphical abstract: Copper(i)-catalyzed N–H olefination of sulfonamides for N-sulfonyl enaminone synthesis

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Jun 2018, accepted on 04 Jul 2018 and first published on 05 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC04385J
Citation: Chem. Commun., 2018, Advance Article
  •   Request permissions

    Copper(I)-catalyzed N–H olefination of sulfonamides for N-sulfonyl enaminone synthesis

    X. Liang, X. Huang, M. Xiong, K. Shen and Y. Pan, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC04385J

Search articles by author

Spotlight

Advertisements