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Issue 65, 2018
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A portal to a class of novel sultone-functionalized pyridines via an annulative SuFEx process employing earth abundant nickel catalysts

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Abstract

An efficient nickel catalyzed annulative process for the synthesis of a class of structurally unique heterocycles containing pharmaceutically important moieties of both pyridines and sultones was developed by using SuFEx chemistry. This mild and efficient method features a wide scope to serve as an irreplaceable asset for medicinal chemistry and drug discovery.

Graphical abstract: A portal to a class of novel sultone-functionalized pyridines via an annulative SuFEx process employing earth abundant nickel catalysts

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Publication details

The article was received on 21 May 2018, accepted on 17 Jul 2018 and first published on 18 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC04032J
Citation: Chem. Commun., 2018,54, 9011-9014
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    A portal to a class of novel sultone-functionalized pyridines via an annulative SuFEx process employing earth abundant nickel catalysts

    X. Chen, G. Zha, W. Fang, K. P. Rakesh and H. Qin, Chem. Commun., 2018, 54, 9011
    DOI: 10.1039/C8CC04032J

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