Jump to main content
Jump to site search


Organic photocatalysis for the radical couplings of boronic acid derivatives in batch and flow

Author affiliations

Abstract

We report an acridium-based organic photocatalyst as an efficient replacement for iridium-based photocatalysts to oxidise boronic acid derivatives by a single electron process. Furthermore, we applied the developed catalytic system to the synthesis of four active pharmaceutical ingredients (APIs). A straightforward scale up approach using continuous flow photoreactors is also reported affording gram an hour throughput.

Graphical abstract: Organic photocatalysis for the radical couplings of boronic acid derivatives in batch and flow

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Mar 2018, accepted on 12 Apr 2018 and first published on 16 May 2018


Article type: Communication
DOI: 10.1039/C8CC02169D
Citation: Chem. Commun., 2018, Advance Article
  • Open access: Creative Commons BY license
  •   Request permissions

    Organic photocatalysis for the radical couplings of boronic acid derivatives in batch and flow

    F. Lima, L. Grunenberg, H. B. A. Rahman, R. Labes, J. Sedelmeier and S. V. Ley, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC02169D

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements