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Issue 57, 2018
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A dual-analyte probe: hypoxia activated nitric oxide detection with phototriggered drug release ability

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Abstract

A new strategy for the detection of hypoxia and NO succeeded by photocontrolled delivery of an anticancer agent has been demonstrated. The developed system is able to produce distinct responses (dual channel) upon interaction with hypoxia and NO. This probe can also release anticancer drugs upon photoirradiation acting potentially as both a dual-analyte imaging agent and a prodrug.

Graphical abstract: A dual-analyte probe: hypoxia activated nitric oxide detection with phototriggered drug release ability

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Publication details

The article was received on 07 Mar 2018, accepted on 20 Jun 2018 and first published on 20 Jun 2018


Article type: Communication
DOI: 10.1039/C8CC01854E
Citation: Chem. Commun., 2018,54, 7940-7943
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    A dual-analyte probe: hypoxia activated nitric oxide detection with phototriggered drug release ability

    S. Biswas, Y. Rajesh, S. Barman, M. Bera, A. Paul, M. Mandal and N. D. Pradeep Singh, Chem. Commun., 2018, 54, 7940
    DOI: 10.1039/C8CC01854E

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