Evidence for anion-binding of all-cis hexafluorocyclohexane in solution and solid state

Abstract

We report a solution NMR and X-ray crystallographic study on the anion affinity of all-cis 1,2,3,4,5,6-hexafluorocyclohexane, which has only recently become synthetically accessible. Our results suggest that the interaction exhibits preferential 1 : 1 stoichiometry, while its strength is only moderate (e.g. K_a = 400 M⁻¹ in acetone for Cl⁻) and depends mainly on the size of the anion and the dielectric constant of the solvent.