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Issue 41, 2018
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In vitro selection of electrochemical peptide probes using bioorthogonal tRNA for influenza virus detection

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Abstract

An electrosensitive peptide probe has been developed from an in vitro selection technique using biorthogonal tRNA prepared with an electroreactive non-natural amino acid, 3,4-ethylenedioxythiophene-conjugated aminophenylalanine. The selected probe quantitatively detected the influenza virus based on a signal “turn-on” mechanism. The developed strategy could be used to develop electrochemical biosensors toward a variety of targets.

Graphical abstract: In vitro selection of electrochemical peptide probes using bioorthogonal tRNA for influenza virus detection

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Publication details

The article was received on 05 Mar 2018, accepted on 24 Apr 2018 and first published on 02 May 2018


Article type: Communication
DOI: 10.1039/C8CC01775A
Citation: Chem. Commun., 2018,54, 5201-5204
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    In vitro selection of electrochemical peptide probes using bioorthogonal tRNA for influenza virus detection

    T. B. K. C., S. Tada, L. Zhu, T. Uzawa, N. Minagawa, S. Luo, H. Zhao, H. Yu, T. Aigaki and Y. Ito, Chem. Commun., 2018, 54, 5201
    DOI: 10.1039/C8CC01775A

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