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Issue 24, 2018
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Correcting the effect of hematocrit in whole blood coagulation analysis on paper-based lateral flow device

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Abstract

A simple method to correct the effect of hematocrit (Hct) on a paper-based lateral flow assay device that is designed to assess whole blood coagulation is reported. By quantifying the effect of Hct on red blood cell (RBC) transport, a calibration procedure is obtained that compensates for the Hct effect, while maintaining the dependence of blood coagulation on RBC transport.

Graphical abstract: Correcting the effect of hematocrit in whole blood coagulation analysis on paper-based lateral flow device

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Publication details

The article was received on 25 Jan 2018, accepted on 15 May 2018 and first published on 17 May 2018


Article type: Paper
DOI: 10.1039/C8AY00192H
Citation: Anal. Methods, 2018,10, 2869-2874
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    Correcting the effect of hematocrit in whole blood coagulation analysis on paper-based lateral flow device

    H. Li, D. Han, Giovanni M. Pauletti, M. A. Hegener and A. J. Steckl, Anal. Methods, 2018, 10, 2869
    DOI: 10.1039/C8AY00192H

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