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A ratiometric fluorescent hydrogen peroxide chemosensor manipulated by an ICT-activated FRET mechanism and its bioimaging application in living cells and zebrafish

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Abstract

A H2O2-responsive fluorescent chemosensor (CNBE) with a ratiometric emission signal was elaborately designed and synthesized. The ratio signal of the chemosensor was manipulated by an interplaying ICT-activated FRET mechanism. The ratiometric fluorescence imaging was successfully applied to detect H2O2 using CNBE in living cells and zebrafish.

Graphical abstract: A ratiometric fluorescent hydrogen peroxide chemosensor manipulated by an ICT-activated FRET mechanism and its bioimaging application in living cells and zebrafish

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Publication details

The article was received on 06 May 2018, accepted on 20 Jun 2018 and first published on 28 Jun 2018


Article type: Communication
DOI: 10.1039/C8AN00842F
Citation: Analyst, 2018, Advance Article
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    A ratiometric fluorescent hydrogen peroxide chemosensor manipulated by an ICT-activated FRET mechanism and its bioimaging application in living cells and zebrafish

    K. Xu, L. He, X. Yang, Y. Yang and W. Lin, Analyst, 2018, Advance Article , DOI: 10.1039/C8AN00842F

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