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Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

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Abstract

Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.

Graphical abstract: Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

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Publication details

The article was received on 17 Apr 2018, accepted on 15 May 2018 and first published on 16 May 2018


Article type: Communication
DOI: 10.1039/C8AN00711J
Citation: Analyst, 2018, Advance Article
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    Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

    X. Feng, J. Ashley, T. Zhou, A. Halder and Y. Sun, Analyst, 2018, Advance Article , DOI: 10.1039/C8AN00711J

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