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Design of a wearable device for real-time screening of urinary tract infection and kidney disease based on smartphone

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Abstract

In this study, we developed a novel wearable and low-cost device for qualitative screening of glucose (GLU), leukocytes (LEU), and nitrite (NIT) and for semi-quantitative analysis of blood (BLD) and proteins (PRO) in the urine samples. The device can be attached to a diaper, and the results can be read by an app. The main functions of the device can be divided into sample collection, valve closing, and pad saturation; the recorded times for valve closing and pad saturation at four corners and pad saturation at the central parts are pseudo-medians (Hodges–Lehmann estimator) of 3.55 (95% WCI, 3.45–3.72), 6.5 (95% WCI, 6–7), and 6 (95% WCI, 5.5–6.5) minutes, respectively. The RGB values in the reagent pads remain stable from 20 min to 480 min, which satisfies the requirement of regular diaper-wearing time. Pre-diagnostic results indicate high accuracy with good accuracy for the app recognition of five biomarkers in the urine samples, which makes it a promising tool for screening diseases, especially for the elderly healthcare.

Graphical abstract: Design of a wearable device for real-time screening of urinary tract infection and kidney disease based on smartphone

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Publication details

The article was received on 26 Jan 2018, accepted on 15 Apr 2018 and first published on 26 Apr 2018


Article type: Paper
DOI: 10.1039/C8AN00157J
Citation: Analyst, 2018, Advance Article
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    Design of a wearable device for real-time screening of urinary tract infection and kidney disease based on smartphone

    J. Zhou and T. Dong, Analyst, 2018, Advance Article , DOI: 10.1039/C8AN00157J

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