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Issue 9, 2018
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Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers

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Abstract

In this communication, we present the first developed Molecularly Imprinted Polymers (MIPs) for the specific detection of a New Psychoactive Substance (NPS); namely, methoxphenidine (MXP) and its regioisomers. Selectivity of the MIP towards MXP is studied by analysing mixtures and an acquired street sample with High Performance Liquid Chromatography coupled to UV detection. The study demonstrates that the engineered polymers selectively extract MXP from heterogeneous samples, which makes for a very powerful diagnostic tool that can detect traces of MXP in complicated NPS samples.

Graphical abstract: Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers

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Publication details

The article was received on 23 Jan 2018, accepted on 11 Apr 2018 and first published on 12 Apr 2018


Article type: Communication
DOI: 10.1039/C8AN00131F
Citation: Analyst, 2018,143, 2002-2007
  • Open access: Creative Commons BY-NC license
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    Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers

    J. W. Lowdon, S. M. O. Alkirkit, R. E. Mewis, D. Fulton, C. E. Banks, O. B. Sutcliffe and M. Peeters, Analyst, 2018, 143, 2002
    DOI: 10.1039/C8AN00131F

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