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Issue 42, 2017
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Complex coacervates based on recombinant mussel adhesive proteins: their characterization and applications

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Abstract

Complex coacervates are a dense liquid phase of oppositely charged polyions formed by the associative separation of a mixture of polyions. Coacervates have been widely employed in many fields including the pharmaceutical, cosmetic, and food industries due to their intriguing interfacial and bulk material properties. More recently, attempts to develop an effective underwater adhesive have been made using complex coacervates that are based on recombinant mussel adhesive proteins (MAPs) due to the water immiscibility of complex coacervates and the adhesiveness of MAPs. MAP-based complex coacervates contribute to our understanding of the physical nature of complex coacervates and they provide a promising alternative to conventional invasive surgical repairs. Here, this review provides an overview of recombinant MAP-based complex coacervations, with an emphasis on their characterization and the uses of such materials for applications in the fields of biomedicine and tissue engineering.

Graphical abstract: Complex coacervates based on recombinant mussel adhesive proteins: their characterization and applications

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Publication details

The article was received on 28 Aug 2017, accepted on 27 Sep 2017 and first published on 27 Sep 2017


Article type: Review Article
DOI: 10.1039/C7SM01735A
Citation: Soft Matter, 2017,13, 7704-7716
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    Complex coacervates based on recombinant mussel adhesive proteins: their characterization and applications

    H. J. Kim, B. Yang, T. Y. Park, S. Lim and H. J. Cha, Soft Matter, 2017, 13, 7704
    DOI: 10.1039/C7SM01735A

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