Issue 59, 2017

Facile synthesis of novel hybrid POSS biomolecules via “Click” reactions

Abstract

A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc-norleucine and (ii) 3′-azido-3′-deoxythymidine.

Graphical abstract: Facile synthesis of novel hybrid POSS biomolecules via “Click” reactions

Supplementary files

Article information

Article type
Paper
Submitted
18 Jul 2017
Accepted
21 Jul 2017
First published
28 Jul 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 37474-37477

Facile synthesis of novel hybrid POSS biomolecules via “Click” reactions

Y. El Aziz, N. Mehrban, P. G. Taylor, M. A. Birchall, J. Bowen, A. R. Bassindale, M. B. Pitak and S. J. Coles, RSC Adv., 2017, 7, 37474 DOI: 10.1039/C7RA07915J

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements