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Issue 52, 2017, Issue in Progress
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Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol

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Abstract

Thiazolines and thiazoles are an integral part of numerous natural products, a number of drugs, and many useful molecules such as ligands for metal catalysis. We report the first common synthetic protocol for the synthesis of thiazoles and thiazolines. Novel molecules are efficiently synthesized by using readily available and inexpensive substrates. The reaction conditions are mild and pure products are obtained without work-up and column purification.

Graphical abstract: Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol

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Publication details

The article was received on 29 May 2017, accepted on 21 Jun 2017 and first published on 26 Jun 2017


Article type: Paper
DOI: 10.1039/C7RA05993K
Citation: RSC Adv., 2017,7, 32647-32651
  • Open access: Creative Commons BY license
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    Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol

    Z. A. Alsharif and M. A. Alam, RSC Adv., 2017, 7, 32647
    DOI: 10.1039/C7RA05993K

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