Issue 24, 2017, Issue in Progress
From the journal:

RSC Advances

Modular synthesis of propargylamine modified cyclodextrins by a gold(iii)-catalyzed three-component coupling reaction†

Tsz-Wai Hui,‡ab   Jian-Fang Cui‡ab  and  Man-Kin Wong ORCID logo *ab  

* Corresponding authors

a The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, PR China

b State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, PR China
E-mail: mankin.wong@polyu.edu.hk
Fax: +852 2364 9932

Abstract

An efficient modular approach for the synthesis of propargylamine modified β-cyclodextrins has been developed. Using mono-(6-benzylamino-6-deoxy)-β-cyclodextrins, formaldehyde, and alkynes, mono-(6-(benzylpropargyl)amino-6-deoxy)-β-cyclodextrins have been synthesized through a three-component coupling reaction catalyzed by gold(III) salt in water at 40 °C.

Graphical abstract: Modular synthesis of propargylamine modified cyclodextrins by a gold(iii)-catalyzed three-component coupling reaction

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Article information

DOI
https://doi.org/10.1039/C7RA00249A
Article type
Paper
Submitted
07 Jan 2017
Accepted
24 Feb 2017
First published
03 Mar 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 14477-14480

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Modular synthesis of propargylamine modified cyclodextrins by a gold(III)-catalyzed three-component coupling reaction

T. Hui, J. Cui and M. Wong, RSC Adv., 2017, 7, 14477 DOI: 10.1039/C7RA00249A

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