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Issue 7, 2017
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Lipid-membrane-incorporated arylboronate esters as agents for boron neutron capture therapy

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Abstract

Arylboronate esters bearing methyl groups in both of their ortho positions were stably incorporated into lipid membranes at high concentrations without undergoing hydrolysis to the corresponding boronic acids. This method could be used in combination with previous methods to increase the maximum ratio of boron atoms in liposomal boron carriers.

Graphical abstract: Lipid-membrane-incorporated arylboronate esters as agents for boron neutron capture therapy

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Publication details

The article was received on 03 Oct 2016, accepted on 28 Oct 2016 and first published on 28 Oct 2016


Article type: Communication
DOI: 10.1039/C6OB02142E
Citation: Org. Biomol. Chem., 2017,15, 1565-1569
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    Lipid-membrane-incorporated arylboronate esters as agents for boron neutron capture therapy

    M. Ueda, K. Ashizawa, K. Sugikawa, K. Koumoto, T. Nagasaki and A. Ikeda, Org. Biomol. Chem., 2017, 15, 1565
    DOI: 10.1039/C6OB02142E

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