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Issue 9, 2017
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Formation of β-(1,3-1,6)-D-glucan-complexed [70]fullerene and its photodynamic activity towards macrophages

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Abstract

[70]Fullerene was dissolved in water by complexation with β-1,3-glucan using a mechanochemical high-speed vibration milling apparatus. The photodynamic activity of β-1,3-glucan-complexed C70 was highly dependent on the expression level of dectin-1 on the cell surfaces of macrophages. The photodynamic activity increased as a result of a synergistic effect between β-1,3-glucan-complexed 1′-acetoxychavicol acetate and the C70 complex.

Graphical abstract: Formation of β-(1,3-1,6)-d-glucan-complexed [70]fullerene and its photodynamic activity towards macrophages

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Publication details

The article was received on 16 Dec 2016, accepted on 02 Feb 2017 and first published on 03 Feb 2017


Article type: Paper
DOI: 10.1039/C6OB02747D
Citation: Org. Biomol. Chem., 2017,15, 1990-1997
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    Formation of β-(1,3-1,6)-D-glucan-complexed [70]fullerene and its photodynamic activity towards macrophages

    A. Ikeda, M. Akiyama, K. Sugikawa, K. Koumoto, Y. Kashijima, J. Li, T. Suzuki and T. Nagasaki, Org. Biomol. Chem., 2017, 15, 1990
    DOI: 10.1039/C6OB02747D

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