Jump to main content
Jump to site search

Issue 4, 2017
Previous Article Next Article

Action-FRET of β-cyclodextrin inclusion complexes

Author affiliations


Cyclodextrin is commonly used in the formation of supramolecular complexes with an array of targets ranging from metal ion sensing to modulation of peptide properties. Many of the applications of these supramolecular complexes are measured by monitoring the modulation of the optical properties of a chromophore upon formation or breaking of the complex. The transposition of these complexes to the gas phase allows their study in a size selected manner, based on the isolation of specific stoichiometries to be analyzed independently. Förster Resonance Energy Transfer (FRET) is used to study the structure of these supramolecular complexes in solution phase. This motivates the use of action-FRET – a recently developed gas-phase extension of the FRET technique – to study the structure of gaseous supramolecular complexes. Here, the feasibility of performing action-FRET on a supramolecular assembly constituted by a chromophore tagged cyclodextrin receptor and a donor chromophore tagged amyloid beta peptide fragment is considered.

Graphical abstract: Action-FRET of β-cyclodextrin inclusion complexes

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Oct 2016, accepted on 23 Jan 2017 and first published on 23 Jan 2017

Article type: Paper
DOI: 10.1039/C6NJ03250H
Citation: New J. Chem., 2017,41, 1806-1812
  •   Request permissions

    Action-FRET of β-cyclodextrin inclusion complexes

    Q. Duez, G. Knight, S. Daly, J. De Winter, E. Halin, L. MacAleese, R. Antoine, P. Gerbaux and P. Dugourd, New J. Chem., 2017, 41, 1806
    DOI: 10.1039/C6NJ03250H

Search articles by author