Jump to main content
Jump to site search


Ligand-induced reactivity of β-diketiminate magnesium complexes for regioselective functionalization of fluoroarenes via C–H or C–F bond activations

Author affiliations

Abstract

Using β-diketiminate Mg(II) complexes containing either alkyl, aryl or amide groups, the regioselective functionalization of a wide range of fluoroarenes is accomplished but in uniquely different ways. Overcoming common limitations of traditional s-block bases, kinetically activated [(DippNacnac)Mg(TMP)] (1) deprotonates these molecules at room temperature, trapping sensitive fluoroaryl anions that can then engage in Negishi cross-coupling; whereas [(DippNacnac)Mg(R)THF] (R = nBu, Ph, benzofuryl) have proved to be effective reagents for C–F bond alkylation/arylation via pyridine directed C–F bond cleavage.

Graphical abstract: Ligand-induced reactivity of β-diketiminate magnesium complexes for regioselective functionalization of fluoroarenes via C–H or C–F bond activations

Back to tab navigation

Supplementary files

Publication details

The article was received on 14 Sep 2017, accepted on 29 Sep 2017 and first published on 29 Sep 2017


Article type: Communication
DOI: 10.1039/C7CC07193K
Citation: Chem. Commun., 2017, Advance Article
  •   Request permissions

    Ligand-induced reactivity of β-diketiminate magnesium complexes for regioselective functionalization of fluoroarenes via C–H or C–F bond activations

    L. Davin, R. McLellan, A. R. Kennedy and E. Hevia, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC07193K

Search articles by author

Spotlight

Advertisements