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Issue 30, 2017
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Controlling transmembrane protein concentration and orientation in supported lipid bilayers

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Abstract

The trans-membrane protein – proteorhodopsin (pR) has been incorporated into supported lipid bilayers (SLB). In-plane electric fields have been used to manipulate the orientation and concentration of these proteins, within the SLB, through electrophoresis leading to a 25-fold increase concentration of pR.

Graphical abstract: Controlling transmembrane protein concentration and orientation in supported lipid bilayers

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Publication details

The article was received on 08 Feb 2017, accepted on 27 Mar 2017 and first published on 31 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC01023K
Citation: Chem. Commun., 2017,53, 4250-4253
  • Open access: Creative Commons BY license
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    Controlling transmembrane protein concentration and orientation in supported lipid bilayers

    P. Bao, M. L. Cartron, K. H. Sheikh, B. R. G. Johnson, C. N. Hunter and S. D. Evans, Chem. Commun., 2017, 53, 4250
    DOI: 10.1039/C7CC01023K

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