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Issue 32, 2017
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Fluorescent polymer prodrug nanoparticles with aggregation-induced emission (AIE) properties from nitroxide-mediated polymerization

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Abstract

Aggregation-induced emission (AIE)-active polymer prodrug nanoparticles were readily prepared by growing short, well-defined polymer chains from an AIE dye by nitroxide-mediated polymerization, followed by co-nanoprecipitation of the resulting conjugates with similarly constructed anticancer polymer prodrugs. The nanoparticles had sharp fluorescence signal offering excellent imaging ability in living cells and their intra cellular localization to be accurately monitored.

Graphical abstract: Fluorescent polymer prodrug nanoparticles with aggregation-induced emission (AIE) properties from nitroxide-mediated polymerization

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Publication details

The article was received on 12 Nov 2016, accepted on 29 Mar 2017 and first published on 06 Apr 2017


Article type: Communication
DOI: 10.1039/C6CC09052D
Citation: Chem. Commun., 2017,53, 4489-4492
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    Fluorescent polymer prodrug nanoparticles with aggregation-induced emission (AIE) properties from nitroxide-mediated polymerization

    Y. Bao, E. Guégain, V. Nicolas and J. Nicolas, Chem. Commun., 2017, 53, 4489
    DOI: 10.1039/C6CC09052D

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