Jump to main content
Jump to site search

Issue 9, 2017
Previous Article Next Article

A cell-permeable and triazole-forming fluorescent probe for glycoconjugate imaging in live cells

Author affiliations

Abstract

A new fluorescence-forming probe, coumOCT, designed by fusing cyclooctyne with a coumarin fluorophore was successfully used for the imaging of azido-glycoconjugates in living HeLa cells. This probe is cell-permeable and generates fluorescence after triazole formation, thus minimizing the background signal and enabling the real-time intracellular imaging of glycoconjugate trafficking.

Graphical abstract: A cell-permeable and triazole-forming fluorescent probe for glycoconjugate imaging in live cells

Back to tab navigation

Supplementary files

Publication details

The article was received on 03 Nov 2016, accepted on 22 Dec 2016 and first published on 22 Dec 2016


Article type: Communication
DOI: 10.1039/C6CC08805H
Citation: Chem. Commun., 2017,53, 1490-1493
  •   Request permissions

    A cell-permeable and triazole-forming fluorescent probe for glycoconjugate imaging in live cells

    J. Shie, Y. Liu, J. Hsiao, J. Fang and C. Wong, Chem. Commun., 2017, 53, 1490
    DOI: 10.1039/C6CC08805H

Search articles by author

Spotlight

Advertisements