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Issue 4, 2017
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A new way to do an old reaction: highly efficient reduction of organic azides by sodium iodide in the presence of acidic ion exchange resin

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Abstract

Organic azides are readily reduced to the corresponding amines by treatment with sodium iodide in the presence of acidic ion exchange resin. The process, optimal when performed at 40 °C and 200 mbar pressure on a rotatory evaporator, is extremely efficient, clean, and tolerant of a variety of functional groups.

Graphical abstract: A new way to do an old reaction: highly efficient reduction of organic azides by sodium iodide in the presence of acidic ion exchange resin

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Publication details

The article was received on 25 Oct 2016, accepted on 14 Dec 2016 and first published on 14 Dec 2016


Article type: Communication
DOI: 10.1039/C6CC08574A
Citation: Chem. Commun., 2017,53, 713-715
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    A new way to do an old reaction: highly efficient reduction of organic azides by sodium iodide in the presence of acidic ion exchange resin

    K. Suthagar and A. J. Fairbanks, Chem. Commun., 2017, 53, 713
    DOI: 10.1039/C6CC08574A

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