Issue 1, 2017

A metal-free fluorescence turn-on molecular probe for detection of nucleoside triphosphates

Abstract

We report a fluorescence probe 1, which contains a naphthalimide fluorophore with two symmetric peptidic arms equipped with a tailor-made anion-binding motif, the guanidiniocarbonyl pyrrole moiety, for the detection of nucleoside triphosphates. Upon binding to nucleoside triphosphates, especially ATP, 1 shows significant turn-on fluorescence response. Probe 1 can also be applied for the imaging of ATP in cells.

Graphical abstract: A metal-free fluorescence turn-on molecular probe for detection of nucleoside triphosphates

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
18 Oct 2016
Accepted
25 Nov 2016
First published
25 Nov 2016

Chem. Commun., 2017,53, 208-211

A metal-free fluorescence turn-on molecular probe for detection of nucleoside triphosphates

D. Maity, M. Li, M. Ehlers and C. Schmuck, Chem. Commun., 2017, 53, 208 DOI: 10.1039/C6CC08386B

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