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Issue 2, 2017
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Novel phosphorescent Mn-doped ZnS quantum dots as a probe for the detection of L-tyrosine in human urine

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Abstract

Phosphorescent 4-morpholineethanesulfonic acid-capped Mn-doped ZnS (MES-MnZnS) quantum dots were developed for sensitively and selectively detecting L-tyrosine (L-Tyr) in human urine. L-Tyr can effectively quench the phosphorescence of MES-MnZnS even at low concentration levels. The mechanism of phosphorescence quenching is ascribed to electron transfer from MES-MnZnS QDs to L-Tyr. Under optimal conditions, the phosphorescent probe allowed a highly sensitive detection of L-Tyr with a wide linear range of 0.5–100 μM and a low detection limit of 0.22 μM. The developed method offers good selectivity over other compounds and was applied to determine L-Tyr in real urine samples with quantitative spike recoveries from 96.7% to 106.2%.

Graphical abstract: Novel phosphorescent Mn-doped ZnS quantum dots as a probe for the detection of l-tyrosine in human urine

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Publication details

The article was received on 25 Jul 2016, accepted on 18 Nov 2016 and first published on 25 Nov 2016


Article type: Paper
DOI: 10.1039/C6AY02107G
Citation: Anal. Methods, 2017,9, 287-293
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    Novel phosphorescent Mn-doped ZnS quantum dots as a probe for the detection of L-tyrosine in human urine

    P. Deng, L. Lu, T. Tan, Y. Jin, X. Fan, W. Cao and X. Tian, Anal. Methods, 2017, 9, 287
    DOI: 10.1039/C6AY02107G

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