Issue 34, 2016

Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs

Abstract

Biocompatible hybrid hollow spheres of calcium carbonate/folate with both mesopores and macropores were synthesized using a facile green approach based on Ostwald ripening. The porous hollow spheres were efficiently loaded with doxorubicin, which they were then able to release in a pH-responsive and sustained manner for the targeted treatment of human cancer cells.

Graphical abstract: Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs

Supplementary files

Article information

Article type
Communication
Submitted
16 Jun 2016
Accepted
24 Jul 2016
First published
25 Jul 2016

J. Mater. Chem. B, 2016,4, 5650-5653

Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs

Y. Guo, W. Jia, H. Li, W. Shi, J. Zhang, J. Feng and L. Yang, J. Mater. Chem. B, 2016, 4, 5650 DOI: 10.1039/C6TB01483F

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