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Issue 15, 2016
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Surface functionalized halloysite nanotubes decorated with silver nanoparticles for enzyme immobilization and biosensing

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Abstract

Improving enzyme immobilization with high loading capacity and achieving direct electron transfer (DET) between the enzyme and the electrode surface is key to designing highly sensitive enzymatic electrochemical biosensors. Herein, we report a novel approach based on the selective modification of the outer surface of halloysite nanotubes (HNTs) that supports silver nanoparticles (AgNPs) to obtain a hybrid nanocomposite. AgNPs of about 10 nm average size could be uniformly supported on silane-modified HNTs through in situ reduction of Ag+ ions. The resultant nanocomposite shows an excellent support capability for the effective immobilization and electrical wiring of redox enzyme glucose oxidase (GOx). The GOx immobilized HNT/AgNPs were deposited on the glassy carbon electrode (GCE) and utilized for the bioelectrocatalyzed electrochemical detection of glucose. The GOx modified composite electrodes show glucose sensitivity as high as 5.1 μA mM−1 cm−2, which is higher than for the electrodes prepared without surface functionalization.

Graphical abstract: Surface functionalized halloysite nanotubes decorated with silver nanoparticles for enzyme immobilization and biosensing

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Publication details

The article was received on 07 Jan 2016, accepted on 09 Mar 2016 and first published on 10 Mar 2016


Article type: Paper
DOI: 10.1039/C6TB00051G
Citation: J. Mater. Chem. B, 2016,4, 2553-2560
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    Surface functionalized halloysite nanotubes decorated with silver nanoparticles for enzyme immobilization and biosensing

    S. Kumar-Krishnan, A. Hernandez-Rangel, U. Pal, O. Ceballos-Sanchez, F. J. Flores-Ruiz, E. Prokhorov, O. Arias de Fuentes, R. Esparza and M. Meyyappan, J. Mater. Chem. B, 2016, 4, 2553
    DOI: 10.1039/C6TB00051G

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