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Issue 2, 2016
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Pot economy and one-pot synthesis

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Abstract

The one-pot synthesis of a target molecule in the same reaction vessel is widely considered to be an efficient approach in synthetic organic chemistry. In this review, the characteristics and limitations of various one-pot syntheses of biologically active molecules are explained, primarily involving organocatalytic methods as key tactics. Besides catalysis, the pot-economy concepts presented herein are also applicable to organometallic and organic reaction methods in general.

Graphical abstract: Pot economy and one-pot synthesis

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Publication details

The article was received on 07 Aug 2015, accepted on 26 Nov 2015 and first published on 06 Jan 2016


Article type: Perspective
DOI: 10.1039/C5SC02913A
Citation: Chem. Sci., 2016,7, 866-880
  • Open access: Creative Commons BY license
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    Pot economy and one-pot synthesis

    Y. Hayashi, Chem. Sci., 2016, 7, 866
    DOI: 10.1039/C5SC02913A

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