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Issue 88, 2016, Issue in Progress
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Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes

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Abstract

Luminescent Mn3[Co(CN)6]2 nanocubes doped with Cd2+ can induce human lung adenocarcinoma cells A549 generating more metallothioneins (MTs) than squamous cells H520. The nanocubes can be bound to MTs and be excluded from cells for detoxification. Then A549 cells have a lower fluorescence imaging intensity than H520 cells, which can distinguish the two kinds of cells.

Graphical abstract: Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes

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Publication details

The article was received on 01 Apr 2016, accepted on 23 Aug 2016 and first published on 31 Aug 2016


Article type: Communication
DOI: 10.1039/C6RA08370F
Citation: RSC Adv., 2016,6, 84810-84814
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    Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes

    J. Chen, M. He, P. Xu, H. Wu, Z. Guo, B. Shi and Q. Chen, RSC Adv., 2016, 6, 84810
    DOI: 10.1039/C6RA08370F

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