Issue 88, 2016, Issue in Progress
From the journal:

RSC Advances

Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes†

Jian Chen,ab   Mengni He,a   Pengping Xu,a   Huihui Wu,c   Zhen Guo,*c   Bingyang Shi*b  and  Qianwang Chen*a  

* Corresponding authors

a Hefei National Laboratory for Physical Sciences at Microscale, Department of Materials Science & Engineering, CAS High Magnetic Field Laboratory, University of Science and Technology of China, Hefei, China
E-mail: cqw@ustc.edu.cn
Fax: +86-551-63603005

b School of Life Sciences, Henan University, Kaifeng, China

c Anhui Key Laboratory for Cellular Dynamics and Chemical Biology, School of Life Sciences, University of Science and Technology of China, Hefei, China

Abstract

Luminescent Mn3[Co(CN)6]2 nanocubes doped with Cd2+ can induce human lung adenocarcinoma cells A549 generating more metallothioneins (MTs) than squamous cells H520. The nanocubes can be bound to MTs and be excluded from cells for detoxification. Then A549 cells have a lower fluorescence imaging intensity than H520 cells, which can distinguish the two kinds of cells.

Graphical abstract: Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes

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Article information

DOI
https://doi.org/10.1039/C6RA08370F
Article type
Communication
Submitted
01 Apr 2016
Accepted
23 Aug 2016
First published
31 Aug 2016

RSC Adv., 2016,6, 84810-84814

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Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes

J. Chen, M. He, P. Xu, H. Wu, Z. Guo, B. Shi and Q. Chen, RSC Adv., 2016, 6, 84810 DOI: 10.1039/C6RA08370F

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