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Issue 6, 2016
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3-Methylene-2,4-chromandione in situ trapping: introducing molecular diversity on 4-hydroxycoumarin

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Abstract

3-Methylene-2,4-chromandione trapped in a solid-state stable Mannich adduct, is released in solution. In the presence of different nucleophiles, this highly reactive intermediate allows the introduction of molecular diversity on C-3 position of 4-hydroxycoumarin.

Graphical abstract: 3-Methylene-2,4-chromandione in situ trapping: introducing molecular diversity on 4-hydroxycoumarin

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Publication details

The article was received on 26 Oct 2015, accepted on 25 Nov 2015 and first published on 26 Nov 2015


Article type: Communication
DOI: 10.1039/C5RA22440C
Author version available: Download Author version (PDF)
Citation: RSC Adv., 2016,6, 4540-4544
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    3-Methylene-2,4-chromandione in situ trapping: introducing molecular diversity on 4-hydroxycoumarin

    A. Montagut-Romans, M. Boulven, M. Lemaire and F. Popowycz, RSC Adv., 2016, 6, 4540
    DOI: 10.1039/C5RA22440C

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