Issue 21, 2016

Well-defined (co)polypeptides bearing pendant alkyne groups

Abstract

A novel metal-free strategy, using hydrogen-bonding catalytic ring opening polymerization of alkyne-functionalized N-carboxy anhydrites of α-amino acids, was developed for the synthesis of well-defined polypeptides bearing pendant alkyne groups. This method provides an efficient way to synthesize novel alkyne-functionalized homopolypeptides (A) and copolypeptides, such as AB diblock (B: non-functionalized), ABA triblock and star-AB diblock, as well as linear and star random copolypeptides, which are precursors of a plethora of complex macromolecular architectures by click chemistry.

Graphical abstract: Well-defined (co)polypeptides bearing pendant alkyne groups

Supplementary files

Article information

Article type
Communication
Submitted
28 Feb 2016
Accepted
17 Mar 2016
First published
18 Mar 2016

Polym. Chem., 2016,7, 3487-3491

Well-defined (co)polypeptides bearing pendant alkyne groups

W. Zhao, Y. Gnanou and N. Hadjichristidis, Polym. Chem., 2016, 7, 3487 DOI: 10.1039/C6PY00365F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements