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Issue 38, 2016
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Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

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Abstract

The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.

Graphical abstract: Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

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Publication details

The article was received on 06 Aug 2016, accepted on 30 Aug 2016 and first published on 30 Aug 2016


Article type: Paper
DOI: 10.1039/C6OB01697A
Citation: Org. Biomol. Chem., 2016,14, 9040-9045
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    Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

    T. Busch, G. Dräger, E. Kunst, H. Benson, F. Sasse, K. Siems and A. Kirschning, Org. Biomol. Chem., 2016, 14, 9040
    DOI: 10.1039/C6OB01697A

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