A novel and facile synthesis of porous SiO2-coated ultrasmall Se particles as a drug delivery nanoplatform for efficient synergistic treatment of cancer cells

Xijian Liu; Guoying Deng; Yeying Wang; Qian Wang; Zhifang Gao; Yangang Sun; Wenlong Zhang; Jie Lu; Junqing Hu

doi:10.1039/C6NR02298G

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A novel and facile synthesis of porous SiO₂-coated ultrasmall Se particles as a drug delivery nanoplatform for efficient synergistic treatment of cancer cells†

Xijian Liu,‡*^a Guoying Deng,‡^b Yeying Wang,^a Qian Wang,^b Zhifang Gao,^a Yangang Sun,^a Wenlong Zhang,^c Jie Lu*^a and Junqing Hu^c

Author affiliations

* Corresponding authors

^a College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, China
E-mail: liuxijian@sues.edu.cn, lujie6742@sina.com

^b Orthopedic Traumatology, Trauma Center, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai 200080, China

^c State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China

Abstract

A novel and facile synthetic route has been developed to fabricate porous SiO₂-coated ultrasmall Se particles (Se@SiO₂ nanospheres) as a drug delivery nanoplatform which combines Se quantum dots and doxorubicin (DOX) for efficient synergistic treatment of cancer cells.

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Article information

DOI: https://doi.org/10.1039/C6NR02298G
Article type: Communication
Submitted: 19 Mar 2016
Accepted: 22 Mar 2016
First published: 30 Mar 2016

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Nanoscale, 2016,8, 8536-8541

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A novel and facile synthesis of porous SiO₂-coated ultrasmall Se particles as a drug delivery nanoplatform for efficient synergistic treatment of cancer cells

X. Liu, G. Deng, Y. Wang, Q. Wang, Z. Gao, Y. Sun, W. Zhang, J. Lu and J. Hu, Nanoscale, 2016, 8, 8536 DOI: 10.1039/C6NR02298G

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