Issue 1, 2016

TCM, brain function and drug space

Abstract

Covering: up to 2015

Traditional Chinese medicine has played a significant role in the mainstream healthcare system in China for thousands of years. Here, we summarize 84 major compounds from 15 selected herbal medicines targeting neurodegenerative diseases. We present a perspective based on the analysis of physicochemical properties of these TCM compounds, and comparison with current drugs and candidates for the treatment of Parkinson's and Alzheimer's disease. The results demonstrate that traditional Chinese medicines contain compounds possessing physicochemical properties that have excellent overlap with developed western medicines.

Graphical abstract: TCM, brain function and drug space

Article information

Article type
Review Article
Submitted
01 May 2015
First published
19 Nov 2015

Nat. Prod. Rep., 2016,33, 6-25

Author version available

TCM, brain function and drug space

C. Tang, Y. Ye, Y. Feng and R. J. Quinn, Nat. Prod. Rep., 2016, 33, 6 DOI: 10.1039/C5NP00049A

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